Thread #42350151 | Image & Video Expansion | Click to Play
HomeIndexCatalogAll ThreadsNew ThreadReply
H
File: hrtgen1.png (1.1 MB)
1.1 MB
1.1 MB PNG
previous: >>42297844

• Help, advice, guidance on meds and dosages
• HRT related medical experiences and research
• Availability and pricing of medications
• Rational and scientific discussion

See following post for a pharmacy list.

Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill ID: https://www.drugs.com/imprints.php
▶ DrugBank: https://www.drugbank.com/
▶ Basic HRT: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ HRT ranges: https://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Powers Method: https://powersfamilymedicine.com/s/Healthcare-of-the-Transgender-Patient-V60.pptx
▶ Endocrine Society Guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ Transline Guidelines (with bicalutamide): https://transline.zendesk.com/hc/en-us/article_attachments/360047702053/TransLine_HRT_Guidelines_FINAL.pdf
▶ WPATH SOC: https://www.wpath.org/publications/soc
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Blood tests (US): https://www.privatemdlabs.com/, https://www.labsmd.com/
▶ Blood tests (UK, Ireland): https://www.medichecks.com/
▶ Blood tests (Canada Only): https://bloodtestscanada.com/
▶ Blood tests (Sweden): https://werlabs.se/
▶ Blood tests by mail: https://www.letsgetchecked.com/ DIY capillary blood samples. Expensive.
▶ Lab test guide: https://www.healthcare.uiowa.edu/
+Showing all 315 replies.
>>
https://www.inhousepharmacy.vu/t-shipping.aspx- Has been popular in the US. Ships from Vanuatu to some countries.
▶ euaibolitatgmaildotcom - Ships from EU to Worldwide.
https://unitedpharmacies-uk.md/(UK only) - Ships from HK.
https://unitedpharmacies.md/(US only) - Ships from HK.
https://alldaychemist.com/- Ships from India to some countries.
https://shape-shifter.webnode.page/- Ships from Turkey to Worldwide.
https://stayhealthynow.co/- Ships from Turkey to Worldwide
https://amazing4health.com/- Ships from Thailand to Worldwide.
https://favskinhouse.com/- Ships from Thailand to Worldwide.
https://goodstuffstore.net/- Ships from Thailand to Worldwide.
https://otc-online-store.com/- Ships from Russia to Worldwide.
https://www.weborderpharmacy.md/(US only) - Ships from India.
https://www.weborderpharmacy-uk.md/(UK only) - Ships from India.
>>
how much finasteride are you supposed to take if you know you're having DHT issues with progesterone? hard to find information on this
>>
File: hrtgen2.png (1.1 MB)
1.1 MB
1.1 MB PNG
whoops, forgot to attach the image, sorry.
>>
Guys, is .25ml 5mg injections every 5 days, and 200mg progesterone daily, hondosing?
i go to planned parenthood
>>
>>42350716
200mg prog is p.normal, hopefully its either micronized or rectal admin
nobody can tell your dosage from the info youve given, we would need ester and concentration, but it doesnt sound that bad to me off vibes
>>
>>42350812
oh im retarded we would just need ester lol
>>
>>42350818
uh idk how to figure ester out?
and the prog is micro capsules orally
what other info do you need? i can pull up my levels and stuff too
>>
>>42350836
i think i gotta use that injectable estradiol simulator? I'll do that real quick
>>
>>42350818
is this the right thing?
>>
>>42350191
i dont know about finasteride but i know about dutasteride, i dont know if that can be useful for you, if you know some conversion between the two, etc
dr powers put his patients facing the same problems at just 1mg of dutasteride per week
>>
>>42350151
what is the best quality e2 injection provider that ships from europe? I dont want to inject from soemone that makes vials in a garage
also, what is the diff between e2 Cypionate and enanthate? why would you choose one or another?
>>
>>42350893
by the way should i be taking my progesterone rectally?
and would planned parenthood be able to notice in labs, or am i fine if i just fib a lil?
i just don't wanna deal with the stress of losing prescriptions temporarily.
fixing that last time after i said some dumb shit was hell.

every 5 days is their compromise... before ot was once a week
>>
>>42351124
sorry nona i got distracted doing some dumb shit irl
yeah youre pretty much fine i reckon, if you want to you can take the prog rectally but if its micronized like u say it wont be much of a difference
congrats ur not hondosed
have fun living the rest of ur life, dont forget to voicetrain
>>
>>42351634
yippy, thanks! I'll try rectally and see if i feel any difference after a few months or something.

when I'm less sick I'll try to voice train, but my throat is egh!
>>
>>42351663
and it says like progesterone 200mg micro capsules on the pill bottle pr whatever
>>
>>42351010
voix celeste and astrovials are the best known ones currently. lena is always there, but i guess you could say she makes vials in a garage.
cypionate and enanthate are functionally basically the same, just get whatever's available
>>
Any injectable testosterone undecanoate DIY in Canada? I have to have long-lasting T due to my job where I will be away for 20 days at a time, flying there and back frequently, can't bring illegal T on the plane
>>
>>42351678
Are the pills little squishy gel capsules? Like can you poke a hole in them and stuff will ooze out?
>>
I am getting the feeling ralox is cope, I just read someone's reddit post about how they low-dosed E, and took ralox, and apparently they wound up with fucking b cups, which is above average compared to another MTF study I read. For fucksake for femboys taking this it really is just gonna be a gamble huh?
>>
>>42353824
yeah
>>
>>42354402
Genetic Lottery
You'll never know what happens till it happens
>>
>>42354535
Okay yeah you can push them up your butt
>>
pg8 bump
>>
how fast to breasts come in, I'm worried about getting too big like say I see them start to grow and I quit HRT will it stop growing(I know it's not reversible)
>>
>>42356638
at month 2-4 buds make going shirtless untenable.

and breast tissue does atrophy a profound amount on testosterone. we tend to underplay how much it is tbhon
>>
How retarded of an idea is it to start HRT to prevent twinkdeath, is it possible to dose low enough i would still like to be able to get it up (also Idc about being infertile) but also high enough to prevent masculinization?
>>
>>42356714
mataining penile function is a thing of using it or losing it rather than dose
>>
how does fat distribution work when starting thin?
i started een monotherapy a week ago and am quite twinky (around 60 kg at 180+ cm) and would really like to get at least some subq fat, and obviously that fat needs to come from somewhere. will the weight i gain now distribute in a masculine way? if so how long should i wait before gaining weight?
>>
>>42350151
is 15mg pio/day gonna do anything or do I need 30?
>>
>>42357898
You don't have to do anything special. Just keep eating normally and taking your hormones.

>>42356714
Low dosing estradiol is always a risky idea. In order for estradiol to work, you need to completely suppress your testosterone to under 30 Ng/dl.

If you do this and low dose estradiol, you might end up having menopause symptoms which are not fun at all. Either go all the way or don't go at all.

>>42356638
Nobody knows and nobody can answer this question for you. This depends entirely on our genetics.
>>
File: kms.jpg (634 KB)
634 KB
634 KB JPG
6mg enanthate weekly, test was done 5 days after injection. my understanding is this number should be a lot higher, right? what do i do?
>>
>>42359966
Are you leaking a bunch of estradiol after administering it?

What's the provenance of your estradiol?
>>
>>42360203
no, none. i've been doing subcutaneous injections since i got this vial 2 months ago, was on pills for several months because i couldnt get a vial sooner. i've been on hrt for years, but i only ever did IM in the past when i have done injections. vial is from opengate distro in canada.
>>
>>42350151
Bump
>>
>>42360442
The only possible explanation that I can come up with is your vial is underdosed or it's degraded from heat or whatever. I'm not a doctor so I can't think of a physiological reason as to why that would happen.
>>
>>42362545
thanks. i'll try 8mg for a few shots and get tested again. what level should my trough ideally be at?
>>
>>42363218
At least 150 pg/ml, if your T is suppressed. Try getting your blood drawn in a different laboratory.
>>
Does HRT make you more depressed or something? I've been off bicalutamide for a few days and I feel idk more alert I guess? Maybe I fucked things up by not doing injections but I don't have a job so it's hard to do blood tests.
>>
>>42359883
Wouldn't testosterone still be made and used by the body since a low dose won't shut down the HPG axis?
>>
When did you guys start noticing changes?
2 months and nothing, starting to get concerned
>>
>>42363908
Testosterone has antidepressive properties. You need estradiol. You have no sex hormone as we speak which is very dangerous.

>>42363920
If you are doing low dose monotherapy, that won't be enough to shut down hpg axis and will greatly hamper feminization.

If you're taking an anti androgen that nukes the axis and are taking little estradiol, that's dangerous.

If it's the former, you'll be running on adrenal testosterone production (DHEA) which is insufficient to prevent menopausal symptoms and all the other complications.
>>
>>42364299
I was only on bicalutamide though and I don't think it shuts down production of testosterone, just blocks it. So I do have a sex hormone.
>>
Is starting prog too soon really bad for you? I really want to try it
>>
did my vials expire or why did my tits shrink after srs
>>
>>42364125
physical? around 6 months lol. it can be a bit earlier and a bit later. but even then was very minor. only now at 13mo i can compare to my pre-hrt pics from like late 2024 and see obvious differences on the face and body
on op guide theres a small effect timeline from when you can expect things to start to happen
>>
I started E in March at 2mg, upped to 4 after 2 months, upped to 6 and added 200mg Spiro at the end of December. Only things I've noticed are my boobs hurting occasionally and having to pee more now. Was I just way too low for all that time?
>>
>>42364125
like a week

what do you mean "nothing"
>>
>>42364299
>If you're taking an anti androgen that nukes the axis and are taking little estradiol, that's dangerous.
depends how little we are talking. isnt estrodiol hrt originally a low dose thing for osteoporosis after menopause?

also i think i read some of the serms or prostate drugs also do the same thing as e for bones and are even prescribed for it (its the no boob one and doubles for cancer prevention in old ladies)

but i agree its a bad idea
>>
>>42367836
nta but

taking low dose estrogen for the 20-30 years after menopause is different than never building up bone density to begin with because you hon dose urself
>>
>>42366361
girl say ur not oral

>>42364781
weight loss?

>>42364400
its more like u wont benefit from it a lot till like a year in
>>
>>42367814
I mean no changes.
>>42365157
thats not fast enough tho
>>
>>42367880
what dose and method
>>
>>42367884
6 mg een weekly
injections, intramuscular
>>
>>42367854
>weight loss?
actually gained quite some weight cause of reduced physical activity
>>
>>42367888
same @ 5mg subq

in like a week i posted asking if i was placeboing myself and it was too early

i was not its extremely noticeable
>>
>>42367909
what was noticeable
theyve been hurting but im 100% sure my nipples havent grown at all or anything. i have pictures of my chest pretransition and theyre the same.
i literally walk around the house shirtless and nobody has said anything
my skin is the same
my cum is still white
is there something wrong with my estrogen
is there something wrong with me
i cant get bloodtests what do i do
>>
>>42367907
nona uuuu might need to check your levels if this is happening bcccc not the besttt
>>
>>42367942
>theyve been hurting
ok thats not nothing.

>im 100% sure my nipples havent grown at all
just the nipples hurt nothing else under or around?

still getting random erections at the same frequency?
>>
>>42367978
there is a stinging pain that comes and goes infrequently in that area. its not really localizable to being under, near, or on the nipple.
in general they are sore and tender
>random erections
i think theyve lessened in frequency? i dont think ive gotten morning wood in a while but im not sure. i fear that im getting them and just am not keeping track of them well.
>>
File: IMG_6636.jpg (375.4 KB)
375.4 KB
375.4 KB JPG
Hey anons

Help please.

Been on 6mg of enn subq for two and a half months. I feel like my trough is too low at 134 even if my monotherapy is suppressing right.
I added more estrogen this week and am continuing on that path, but I’m also leaking a lot of estrogen out when I inject.

Is the leaking a problem and how do I fix that? Are my levels ok or how could I minimize max further? I kinda rely on community knowledge and am just doing this totally DIY. I’ve had noticeable effects from hrt like face looking better, low bo, changes to sperm, noticeable chest development my friends have commented on etc. but I want to do more
Was aiming for a 300 trough.

Thanks for the help!
>>
>>42368008
well thats certainly not nothing
>not keeping track of them well.
idk maybe starta boner journal lol it could just a date and an x or checkmart
>>
>>42350151
I feel like my progress has stalled. 245 pg/ml E and 11 ng/dL T the last time I checked at trough. Been on monotherapy for the past 5 months and been on hrt for 11 months. What should I do next?
>>
>>42367954
impossible for me at the moment.
using a vial from otonoko from 2024 might just be the best idea ig? lel
>>
>>42357898
Patience. There's not really a way to 'game' it as it takes about a decade for all your current fat cells to die and be replaced entirely. You are still replacing them all the time since they're not all made at once, but it's going to be a gradual process. Pretty much everything in transition is a gradual process. HRT? Takes about 5 years at least to 'finalize.' Hair removal? Gonna require multiple sessions over the course of months or a year. Surgery? Getting assessment and referral letters written can take a few weeks to get fully done, getting a consultation date can take upwards of half a year, and getting an actual surgical date can often be more than a year off. Recovery from surgery? Weeks to months before functional again, upwards of a year to fully heal everything.

Patience. Best thing is to let the hormones work their magic while you focus on other things in the meantime, like the social aspects, savings, and other general real life stuff. One of the hardest unsung things about this is accepting that you're just gonna have to wait a lot of the time, at least for me since I hate not being able to keep going/keep pushing for something for reasons outside of my control. I'm addicted to the grind, so I just try to turn my attention to stacking cash in the 'wait' periods between milestones.
>>
>>42368040
>boner journal
unironically a good idea ill start doing that
>>
>>42354402
Bear in mind that a lot of people saying they grew this that or the other cups are obese and already had them, or they're measuring wrong due to having a larger upper torso than an AFAB.
>>
>>42363218
It's a better idea to inject more often than to inject more volume, the half life doesn't change, even though it feels like the larger volume would take longer to be absorbed.
>>
>>42350151
i had a gnrh injection but my nurse fucked it up and spilled like half, now Im paranoid about remasculinizing, my endo told we could see AA pills next time we meet which is like 1 month and a half since I took the injection
should I just buy a vial and do monotherapy?
Im going crazy I think my T is already going up
am I gonna die if I inject estradiol when there is already a gnrh in my body
>>
>>42367836
I think that only applies to real women.

>>42368013
Switch to intramuscular. Oily substances were never meant for subcutaneous. When injecting, add 0.05ml of air to seal the injections site and push out all the oil in the dead space.

>>42368044
Do nothing and continue doing what you already doing. Changes are cyclical.

>>42369358
Well you should have made a scene right then and there and askes to talk to the nurse's boss or something. I would contact your doctor and explain what happened. Tell him the name of the nurse.
>>
>>42369714
And keep the needle inside the injection site for 5 to 10 seconds before taking it out so that the liquid inside has the time it needs to equalize the positive pressure that the liquid itself created when it was injected.
>>
>>42369358
Can you buy spironolactone? Take 50 mg a day. It will probably keep things low for the time being.
>>
bump
>>
Prog is far away for me but I wanted to check in with eurotroons abt prog.
Do docs here prescribe prog? Country is hell on earth (netherlands)
If not, is there any EU based shop to buy it online? I'm already doing diy for my estrogen so it would just be another thing i can do myself.

Also are bloodtests like, super necessary? GPs here don't give them without a cause and privately it's pretty pricey. My tits are developing and my body is reacting to the hrt as it should so I kinda don't see a reason to waste that much money on a test when the meds are doing their job.
>>
injecting sub.
which angle? used to do it straight, is 45° better?
should i release the pinched skin b4 pushing or after?
does ass or thighs matter?
is pushing slow better?
how important is moving (not wiping) the skin afterwards with alc wipe?
ty!
>>
>>42350151
Where can I order Pio if I live in the US?
>>
>>42369747
Will do, appreciate your advice. Will still try subq because of the needles I own but if I have continued issues I’ll do inter musc like you suggest. Thank you <3
>>
i'm scared of going to the dentist and getting my wisdom teeth pulled
should i tell them i'm on diy hrt? will i die if they sedate me because i didn't tell them i'm on estrogen
>>
>>42371030
If you're doing intramuscular, make sure the tip of the needle is aiming upwards if you're injecting into your vastus lateralis. This way the needle will go inside through the muscle fibers. If it goes pointing sideways, it will just destroy everything in its path and will probably increased the chances of having scar tissue in your muscle long-term. Have two spots on each leg.

>>42371071

You should definitely tell your physician when you're doing anything that involves blood. Estrogen increases the likelihood of blood clots. Being high on estrogen and doing a surgery of that kind is always unwise. Yes, I'm suggesting you quit estrogen for one month before doing anything like that.
>>
>>42371138
>Yes, I'm suggesting you quit estrogen for one month before doing anything like that.
that's what they say for ffs but didn't they change their opinion on that
also ideally it would be local anaesthetic
idk i'm just scared as fuck of telling them since i don't pass and i am a hon
>>
>>42367854
>girl say ur not oral
is 6 and 200 still low? that's like the max dosage I've seen basically everywhere. don't just say if it's not injections it's useless
>>
>>42371210
Well it's far more intelligent to go through the humiliation of telling them that you are a transsexual then having to deal with being half brain dead in case the clot goes to your brain and apparently you will not be anywhere in your hospital anyway. Do the right thing, tell them, get it done and probably never see them again. Shit happens and I'm sorry.
>>
>>42371345
i haven't even gone to a dentist because i'm scared they'll find a cavity or smth
i'd tell them but i'm scared
i literally am diy because i'm scared of telling people
>>
Any alternatives to clobetasol for breast growth?
>>
>>42371394
The sooner they find what's wrong with you the less expensive it will be and the less it will hurt. You really don't want to postpone this.
>>
>>42371469
well i'm scared about my next checkup
>>
>>42350191
the odds of having DHT issues with progesterone is super fucking slim, so i really doubt you are.
with that said, 1mg daily should be fine.
>>
>>42350191
Take Dutasteride instead. Finasteride does not block the (rare) prog -> DHT conversion

t.ranny with that particular issue
>>
>>42372063
Do not postpone it.
>>
im posting cuz my boobs are too small. someone said in another thread that the "powers method" might help? im on 200mg prog daily (orally cuz i was really sick, may swap back soon, did do prog the other way but someone said i was pushing it too high??)
>>
>>42371210
haha im gonna beg for local and not tell them lol im not blabbing my ass off on propofol or we
>>
File: file.png (101.4 KB)
101.4 KB
101.4 KB PNG
https://pghrt.diy/#S5.SS7
>>
File: file.png (75.1 KB)
75.1 KB
75.1 KB PNG
>>42372337
¯\_(ツ)_/¯
>>
Two questions, If I have been drawing from one of my spare vials, should i just start using that or can i just leave it and it wont expire. Lastly, should i switch to IM if i notice the bumps from subq are not fully "dissolving" till a couple of days after my next shot. Im thinking that since i can feel the bump from the previous shot, that means my body hasn't fully processed it because it was in fat.
>>
My titties are becoming visible from the front again and they look round instead of like gyno now!! I'm so happy!!
>>
Where can I get some progesterone online and do I need to use crypto or is it not that shady? I'm tired of asking for prog at planned parenthood and those bitches ignoring me every time.
>>
>>42372310
i'm more scared of anesthesia and going to the dentist than getting my teeth pulled
>>
>>42370946
healthyareastore is where I got mine
>>
>>42373275
I do it without crypto because i can't get any rn, you can find sources that take bank transfer but they're in the minority and usually more expensive, crypto seems more convenient
>>
>>42370818
45º for subq
after removing the needle
not really. you can do it around your navel area too. do where you feel more comfortable with
injecting slower? if so yes you always should do that, never do it in just 1 second
just gentle press your injection site with a cotton ball after removing the needle. no need to do a massage, or wiping, nothing, just gentle press it for some seconds
>>
Ever since I started HRT I've been getting this occasional tingle in my nether regions, maybe once or twice a day, kinda like the feeling when you gotta piss
Is this normal? What is it?
>>
Hey I'm kinda worried I'm like under dosing myself on diy pls advise. I've been doing 6mg estradiol enanthate injections every week for the past 13 weeks and I feel like other than tiny breast buds that're like just barely wider than the width of my nipple I really haven't seen much progress :(

I got labs done but they forgot to include my e2 :/ At trough (morning of my injection day, before my shot) my results were:

T 45.5 ng/dL (1.58 nmol/L), LH 0.19, FSH <0.11 (mIU/mL)

It's nice to know my T is suppressed but like could it be that my e2 isnt high enough? Idk it's all so stressful if anyone has any advice pls let me know, thank you
>>
>>42375891
@ 6mg ur not hondosing urself. i know its a meme but bide ur time and weight cycle

>>42373275
its not the easiest. there are crypto exchanges that don't require you to link a bank account though

>>42372261
applicably this is probably refferring to powers referencing adding oral estradiol (2-4mg) to patients who have been on injections without new breast growth for a prolonged period. i have not tried this but he says that some cases can see a jump restart.

oral progesterone also doesn't do very much. i don't think pushing it too far is really a thing. i suppose douching could ensure all the solution gets absorbed into the colon wall.

past that, pioglitizone and clobetasol cycling might be worth looking into. I would only recommend these after a couple cycles.

>>42372089
>>42350191
Dutasteride also notably does not block the backdoor metabolizations that bypass testosterone. the way you block those is with copious amounts of spiro (blocks dht absorbtion) or taking a synthetic metabolyte of progesterone (hydroxyprogesterone) with no androgenic potential
>>
thank you for the help everyone, i decided to go with injections instead of pills on your advice, i was scared at first but surprisingly it feels like nothing at all to be injected intramuscularly, like not even a prick, and its so much cheaper, easier to take and everything
as long as my plunger is at 0ml and empty when i pull it out and theres no moisture/leakage on my leg, i shouldnt worry right? im not getting any bleeding, bumps or any sensation at all other people mention which almost makes me wonder if im not injecting right or something
>>
Should I wait until my breasts are at a tanner 3 to start taking progesterone? I'm on about month 6 of HRT. The breast mound itself is only starting to look larger than the areola and be visible from the front.
>>
>>42376449
thats what current best practice is yes
>>
Are informed consent clinics worth it or should i just DIY? There’s a planned parenthood near me that does informed consent, and i figure I might give it a shot. I want to start injections right away instead of fucking around with hondosing, is there enough flexibility with these places that they’ll let me have a say? Can i ask to start on injections or are they just gonna give me the usual 0.0001 microgram of E and tell me to fuck off?
>>
>>42377152
planned parenthood isnt the worst but they will likely hondose u a little bit

if ur on medicare, they will be cheaper than diy, but not less painful (the concentrations of estradiol they prescribe are lower than diy manufacturers produce).

id say if u wanted to be a pillhon they are preferable, but if you want injections, then DIYing is betterrrrr
>>
>>42350151
reminder for people doing homebrew HRT, check your calculations carefully.
found out I've been giving myself 10x higher dosage of E than I thought because I fucked up my maths making estrogel
>>
>>42377180
That’s what i was afraid of. Oh well, i guess DIY is the best way to go. I’m just such a lazy and stupid fuck, i always forget to take me medication so staying on top of things and figuring out my ideal range will be annoying. Gotta do it if I don’t wanna be a hairy man in a few years so guess I’ll just learn.
>>
>>42350151
post orchi of about 3 months and im struggling to find what levels i feel the best at. currently doing 3mg een every 7 days, but should i try something like 4-5mg every 14? or maybe every 10 days? libido is kinda ass and id like to fix that
>>
the image mentions testing for dht when masculinization continues while on hrt. what should i do if it comes out high? are there any ways to suppress it?
>>
>>42372145
i'm not due for a checkup for a while i just really don't want to do it
>>
>>42376407
Apparently there's nothing wrong happening. Do that for 8 weeks and then have your blood drawn. Remember to rotate your injection sites as to prevent the formation of scar tissue in your muscle and, if you're injecting in your vastus lateralis, make sure the opening of the needle is aiming upwards so that it doesn't destroy as many muscle fibers.

>>42372831
You should keep your vial in the fridge so that the temperature doesn't fuck with it. Buy a skin care fridge if you can.

Oil substances were never meant to be injected subcutaneously. Switch to intramuscular if you can.
>>
>>42379461
>You should keep your vial in the fridge
what's the optimal temp? i keep mine in room temp range (i have a room thermometer to track)
how long is it supposed to last
>Oil substances were never meant to be injected subcutaneously. Switch to intramuscular if you can.
nta but my needles are too short to do im and i'm probably too stupid to do im without fucking up
>>
>>42350151
you're done blud
>>
>>42379461
>Oil substances were never meant to be injected subcutaneously.
why do you keep saying this. never meant to is different than not approved by the fda or paid for clinical trials. the whole point of them being oil is that they dissolve in fat, which is what is under the cutaneous layer, ie subq fat.

like i get it if IM is easier, but its not, or more effective, but its not. were doing DIY here and youre all "But the patent was only approved for IM" so what?

unless im missing some data from a study you havent posted?
>>
>>42381024
I mean in terms of absorption and the post injection site reactions. Both work, yes, but intramuscular is just more appropriate.
>>
File: file.png (109.3 KB)
109.3 KB
109.3 KB PNG
>>42381139
>I mean in terms of absorption
do we have some side by side studies with blood level curves or just speculation?
>post injection site reactions
such as?

not trying to be rude your advice just conflicts with info ive been given and i think it might lead to people hesitating thinking they are doing something wrong or have the wrong equipment

https://pubmed.ncbi.nlm.nih.gov/36868378/
>>
>>42378609
sadly u have to do that with a doctor anyway

>>42378799
i honestly dont THINK making your E levels lower will help with libido

>>42380313
subq is fine for most people nona


>>42378852
DHT treatment it really depends on the source of that DHT. bombarding your body with spiro to block the DHT from being used by your body will do the job, but if you have T in your body as well you might have other issues too

what are your levels and importantly all medications and masculization symptoms?
>>
>>42350151
anyone here know if otoko plans to restock prog?
theyve been out for months
>>
>>42381242
I'm talking about speed at which the medication reaches the blood. Reactions such as a lump which I only see some containers users complaining of.
>>
>>42383198
I mean, subcutaneous users.
>>
is there any way to do blood tests without people knowing you're a troon
like anonymously or whatever
>>
>>42384500
the lab person will know and nobody else. they also won't care.
>>
>>42384618
i dont want them to know :(
>>
>>42383198
well yeah thats normal and how it works

https://en.wikipedia.org/wiki/Depot_injection
>>
>>42381752
this, same with opengate =.=
>>
>>42381285
>i honestly dont THINK making your E levels lower will help with libido
well a few weeks ago i was on 2mg every 7 and it seemed to be a bit better. but ive also noticed at much higher troughs (300-400pg/ml), ill have times where im pretty feral. not sure where to go from here since post-orchi things have just kind of completely changed since i dont have to worry about suppression
>>
>>42371296
the problem is that oral e is unsuitable for monotherapy and you weren't on spiro for 8 goddamn months, that's effectively 8 months of wasted time
>>
is there a way to fix tubular tits? I haven't done blood tests in a while so idk my current levels and I will get some done soon but they used to be ok 2 years in 4mg ev/ 5 days since the beginning no prog
my tits used to be normal looking with a bit of bulging at the nipple in one of them which everyone told me was normal but now after some time of not looking at them in mirror for dysphoria reasons they seem to be going tubular in very visible way so can I still fix them with prog or wearing bras more/less often or massaging or anything else? I really need some help here while I wait for a visit to my endo
>>
>>42384626
Speaking to you as someone that works in a medical lab, they probably won’t know either. I deal with thousands of patients a day, unless you jump out somehow (absolutely fucked levels or you happen to have a really really funny name), nobody will probably even bother to look at your test and it will auto-verify without anyone even clicking on jt
>>
>>42384874
I'll just stop advising SQers.

>>42388331
I've seen real women with that same problem. There are surgeries but I haven't heard of much being able to be done. Sorry.
>>
>>42388585
they are still developping though so isnt there any way to course correct the growth and minimalize it at least?
>>
>>42388648
I'd talk to a mastologist, in addition to an endo. Make sure you find one who knows their shit about trannies
>>
File: repressss.jpg (929.5 KB)
929.5 KB
929.5 KB JPG
Can i feminize my face and only my face?
>>
>>42390140
ffs?
>>
>>42390140
No. Estrogen will go everywhere and it will feminize everything (including your brain).
>>
>>42388355
what constitutes "absolutely fucked levels" more than high E as a male?
>>
switching to diy because i moved out of state, am currently unemployed (but searching for jobs) and dont have health insurance and its just cheaper. Currently doing 4mg of EV every 7 days which is fine cause i dont have testicles anymore (levels good). I got the open gates lab EC. Anyone know about how much EC i should take every 14 days roughly match 4mg of EV weekly? or help me figure it out?
>>
>>42390839
2.5mg EC/7 days would get you the same trough, but 4mg EV weekly is already pretty low https://estrannai.se
>>
>>42390839
>>42390886
i'm a retard and didn't see the 14 days bit, 6.9mg EC/14 days then
>>
>>42390902
lmao I was gonna say cant do 7 days cause 2.5mg is like .0625mL at the concentration i got, my troughs at day 7 with EV at 4mg/7days were about 140-160pg/mL consistently which is fine with me since i dont have testosterone to supress it was like single digits in my blood work, ty
>>
Is 4mg enanthate injection a week a light dose or does it sound about right?
>>
>>42392094
should be fine for most but if you can you'll want to check your trough levels and adjust as needed
>>
>>42392094
Also, is there much of a difference between subcutaneous or intramuscular? I keep finding conflicting info between whether SC or IM is more consistent.
>>42392121
Sweet, it's only been two weeks since I started, should I wait until the 90 day mark like most sources say or just get it done whenever to start with?
>>
>>42392142
See >>42381242
>>
>>42392262
Interesting. Thanks. I might swap to those easy-inject diabetic needles then if that's the case.
>>
pg9 bump
>>
>>42354402
Wait b cups are considered above average for girls like us? Here I am moping I only had bs
>>42356671
Does it I had a little bit without my meds and mine didn’t shrink at all.
>>
Haven't taken E in 5 years. Thinking about getting back in the game.
>>
Am I getting hondosed? currently on .25 ml Estradiol Val Sub and 200 mg Prog........

I'm thinking of going DIY soon, but rn things are fine with my provider, but I also hear sometimes endos don't know anything.
>>
>>42397038
You have to include what concentration the estradiol is as well for people to have any idea if that is a hon dose. It should say on the vial.
>>
>>42397047
Ah sorry 20mg/ml vial
>>
>>42397069
post injection frequency as well as any levels you've previously taken and timing of blood tests
>>
>>42397169
I inject every 7 days with blood test every 3 months. I was supposed to do blood work again around this time but since I got a sudden dose increase I was told to wait. My last blood work came back as estrogen at 258 pg/ml and testosterone at 11 ng/dl. this was just on .22 ml ev nothing else just been frustrated since Im already a year on hrt and almost a year on injections in April and I feel like ive gotten no real progress
>>
>>42397212
When I first started I was on .15 ml then went to .18 ml then .22 ml been increasing steadily always told my blood work is fine always ranged from 240 to 250 with testosterone always being under 50 highest was at 21. I alwasy try and take my blood work 3 to days after injection too
>>
is it bad if I start injections while still having a gnrh in my body?
IDRK when it is gonna wear off
im this anon >>42369358
should I just low dose 5mg every 7 days some weeks?
I have been on 2mg sublingual daily and gnrh every 3 months, for 3 months, my last gnrh was supposed to be my 2nd dose
>>
What should my levels be at if I test at 4 days into my 7 day cycle? I had 400 estrogen and 20 testosterone
>>
>on subl E and bica
>E2 205 pg/ml, T 15 ng/dl, DHT 28 ng/dl
>high dht, start duta
>E2 360 pg/ml - T 25 ng/dl, DHT 14 ng/dl
>in 5 months
>E2 276 pg/ml, T 23 ng/dl, DHT 18 ng/dl
>increase duta to 1mg because too high DHT
>E2 381 pg/ml, T 56 ng/dl, DHT 11 ng/dl
>switch to injections, still 1 mg duta and bica, in 3 months blood test
>E2 650 pg/ml, T 21 ng/dl, DHT 20 ng/dl
>lower injections a bit, try 150 mg bica since transition is not going well and dht is too high and maybe bica would help and increase duta to 1.5 mg
>5 months later
>E2 490 pg/ml, T 18 ng/dl, DHT 18 ng/dl, FSH undetectable, LH undetectable, DHEA-S 169 µg/dL, SHBG 124 nmol/L
>in 5 more months
>E2 421 pg/m, T 21 ng/dl, DHT 41 ng/dl, FSH undetectable, LH 0.13 mIU/mL, DHEA-S 163 µg/dL, SHBG 90 nmol/L
>decide high dht is probably a fluke as it hasn't been that high before, increased bica did nothing so go back to 50 mg, increased duta did nothing so go back to 0.5 mg
>in 5 months
>E2 412 pg/ml, T 22 ng/dl, DHT 118 ng/dl (1181 pg/ml), FSH undetectable, LH 0.39 mIU/mL, SHGB 135 nmol/L, Cortisol 378 nmol/L


i am guessing it's not a mistake since my DHT was higher than ever before already 5 months ago, what does one do in such a situation
should i blood test for anything specific when i re-bloodtest this at a different lab which is what i still assume i should now do
>>
>>42401118
are you getting dht effects? like noticeable ones atleast


>>42399566
depends on ester. and also test at trough so u know how low u go

>>42397383
no girl u need estrogen. 2mg sublingual is fucking nothing
>>
>>42402126
not that i can see, if not counting general lack of fat redistribution or breast growth in 3 years of hrt
>>
>>42402203
girl no fat redistro? be real with me rn
>>
>>42402334
are you doubting my claim or are you saying that that's not something that's related or serious
yes little fat redistro, i tried weight cycling etc, little is not none but little is literally little when i say it here, mostly male distribution after weight cycling etc, that plus again barely any breast growth. is that dht related - i don't know, it COULD be from what i understand, i don't know why else it could be, and i seem to not be getting facial hair/balding at this time at least but i am on bica and also like it is a real blood test result that i got and i'm just worried because it seems like not a false result and my dht has been high the whole time ON duta so like, and now it's at higher than cis male levels apparently
>>
Does weight cycling actually do anything without utilizing malnutrition and obesity? Or are those necessary to accelerate fat redist
>>
So how do I switch HRT? I've been on 12.5mg of cypro and 4mg of progynova daily but now have a way to make the switch to injections, do I like give it a day for the previous hrt to make this safer? I'm not sure if it's my paranoia but my right hand is pretty red for some reason(some stinging pain) so I'm probably gonna bring that up during my blood test in a few days, if it was a blood clot would it get worse? Sorry if I'm acting too worried about this.
>>
>>42403045
i can only help you with the HRT switching anonette, sorry:
just do it! no problem in just switching it tomorrow. the half life of pills are very low anyway
>>
thoughts on progesterone cream vs suppository? im trying to titsmaxx. ive heard before about cycling two weeks on, two weeks off, but what are the benefits of that compared to taking it daily?
>>
>>42402680
u wont do permenant damage from malnourishing yourself if ur over like 16 and yeah dont get too obese on cycles
>>
Mtf here, has anyone tried topical test? Call me faketrans I guess but I'm having pain with arousal that I cant seem to get rid of and I'm wondering if topical t would help. It happens even if I'm not touching myself so I don't think I could even bottom or anything and it makes me sad that I might not be able to have any sort of sex life ever. I've tried the usual advice of "use it or lose it" and I've tried not using it at all so idk what the problem is at this point.
My main concern with topical t is raising serum t levels by a huge amount and fucking over my transition. Most of the info surrounding this online seems to imply this wont happen but I don't understand how that could be possible if ftms are taking topical t to transition. Anyone have any papers i could take a look at or other authoritative sources?
At the end of the day, if I have to choose no pain or transitioning I'll choose transitioning every time but it would be nice to have both.
For reference my levels at last bloodwork were:
E: 470 pg/mL
T: 33 ng/dL
DHT: 11 ng/dL
the only med i'm on is .25 mL of 20 mg/mL valerate every 5 days
>>
>>42350151
My voice was always high and I always get called MA'AM. One year on HRT and now I moan like a bitch and feel fucking good about it.
>>
Mom always wanted a daughter
>>
HRT bump
>>
>>42408859
mine didnt
she had 3 boys
two of them arent boys now
>>
Current best source for pio in the US? I was getting 90x30mg from UnitedPharmacies for only $15, but they discontinued it and now the next-best price seems to be $60 for the same quantity (12 boxes of 7x30mg for $5 each, which would be a massive box for just 30 day supply). Is there anywhere else cheap I can source it from, or should I just suck it up and buy the higher priced one? It looks like made-in-china might sell bulk powder, but that site kind of scares me
>>
>>42411398
Looking for this as well.

Anyone have experience with hydroxyprog injections? Interested in them as an alternative to prometrium but want more than just 1 person's experience on them.
>>
>>42411398
>>42411743
Healthy Area Store has them under Utmos at $27 for 30 days of 30mg
>>
I started een injections (4-5mg) weekly last march. broke my vial in june and couldn't get another until august. So as of now I've been on for 9 months total elapsed, 2 month gap, 7 with estrogen.

As of now I'm around 34B. not sure how good this is at this stage. looks around tanner 3.

My main question, with that background info, is when should I start prog/pio (150lb 5'10", so i think i'm fine weightwise?)/glucocorticoids? I hear people say a year for prog, but how does that work with my 2 month gap. No idea about pio or anything else

tysm
>>
>>42350151
does anyone have a link to the pio server? I saw a lot of discussion about it in >>42388601 and im curious
>>
>>42412452
i second this
>>
>>42412459
>>42412452
bump
>>
>>42411001
Fascinating
>>
Is everyone detransitioning or what?
BUMP
>>
I imagine it’s too late for me to do anything, but my breasts have been stuck with an areola mound I started hurt 13 years ago, I currently take 100mg prog daily but have noticed no difference
>>
starting to low run on prog due to insurance issues, is it worth cycling every 2 weeks on and 2 weeks off rather than continuous administration? related, anyone here tried hydroxyprog injections on a similar cycle and saw benefits over suppository administration? and if so, what needle gauge do you use to draw/inject it?
>>
>prescribed EV 0.25ml every 5 days
>fine for a year
>have to buy new needles online
>latest prescription runs out after second injection
>realize i accidentally injected 2.5ml my last two injections days
lolol i have 100mg of estradiol in my body rn how bad is that? is it being converted into androgens or some shit
>>
>>42416263
how are you feeling nona?
>>
>>42416297
i would also like to know how you're feeling lmao. what's your mood? i personally get horny at peak E2, does that scale?
>>
>>42350151
I'm really shitty at math and I'm switching from 20mg/ml to 40mg/ml. my usual dose is 0.25ml a week, what should it be once I switch? 0.125? 0.1?
>>
>>42416355
0.125mL
>>
>>42416263
e doesn't aromatize into t but you're probably spiking your shbg to hell and back at the minimum
what size syringes are you even using to inject that much? most ppl use 1ml ones and at that dose, you should too
>>
>>42416297
>>42416308
unstable as all fuck. I'm cycling between listlessness, anger and excitement throughout the day. also pretty horny, but not outrageously
>>
>>42416388
how do you even stabilize onto an injection cycle after something like this? skip a week or two and start up again?
>>
>>42416397
in theory your trough 15 days after your last injection should be around the same level as you'd usually be after 5, you can just resume injecting 5mg every 5 days at that point. play around with the "custom doses" section here https://estrannai.se
>>
>>42416384
the new syringes are 3ml. I genuinely just did not notice I bought syringes that were 2ml bigger than usual.

>>42416397
I have no idea. I think my trough is like ten times as high as it usually is (1500 pg/mL). ill probably have to skip two weeks or so anyways, my dumb retarded ass injected the entire vial essentially and my new insurance doesn't want to cover my prescription anymore, so I'm gonna have to scrape together $115 to pay these people at the pharmacy
>>
legitimately the more I think about it, the more horrified I feel. I actually don't know how long I've been injecting 2.5ml lolol I'm gonna ask my PCP to schedule a blood test later today
>>
>>42416438
you're talking about those 100mg (5ml at 20mg/ml) EV vials right? diy is significantly cheaper both per vial and per mg, i'd look into it if i were you (400mg aka 10ml at 40mg/ml for a typical vial as well). it's good to have a diy backup vial on hand anyway for that exact scenario
>>
What is a hon dose?
>>
>>42416619
anything that doesn't bring you into the average or above average blood levels of a cisgender person your age.
>>
why tf my injection keeps leaking out i dont know what i'm doing wrong
>>
>>42417049
run us thru ur entire injection process nona
>>
Help.
I know I'll look like a retard but whatever.
I'm 18 and a twink (60kg, 169cm) and the only estrogen I have access to is the oral conjugated estrogens which I know is shit but that's what I have for now. I also can't let my boobs to grow (they wouldn't anyways) because firstly I'm too ugly to pass and secondly, where I live, others noticing that I'm growing boobs wouldn't be so desirable.
so I thought I'd go with CPA + CE + Ralox but I don't know how to dose them without fucking myself up.
I know this is far from ideal but that's the best I can do for now at least.
also, I'm worried that in the future I'd have to confess about this to doctors or otherwise I'd probably get myself into a real mess.
so, is there any hope for me or I should just kms?
>>
I'm seriously considering diy orchie. What's the least bad way to go about it? Obviously, official means are impossible.

What if I incision my scrotum open, use a sanitized razor to chop them off in a hospital bathroom and then run out screaming bloody murder so that they fix the bloody waterfall coming out of my middle parts? I'm insured, for all that matters.

I've also heard of stirring? Any guides on that?

Something peroxide injections inside the balls? I've heard about it.

I need a feasible method that I can carry out to permanently nuke my HPG axis off the fucking planet.

Help.
>>
>>42418122
umm i just prepare my dose, make sure there are no bubbles in the syringe, pinch somewhere the top of my thigh, carefully insert the needle all the way in and i inject.
then i slowly pull it out, let go of my skin and press the area with a tissue.

sometimes it leaks and sometimes it doesn't. i've found that 90 degree angle works better for me because i tried angling it a bit today and it leaked a bunch. next time i think i might wait a bit longer before pulling it out and let go of the skin before i do it
>>
Is 50mg spiro and 2 est a good dose to avoid breast growth? I want to start but I'm concerned about looking like a man with tits
>>
>>42418722
Don’t I tried when I was 14 it’s painful and there’s too much blood
>>
>>42418873
Are you switching needles for drawing and injecting?
If so, are you ensuring that the injection needle is completely full of liquid before injecting so that you're not injecting a needleful of air?
I know you said you're getting all the bubbles out but when I started this is something I didn't think about and later realized that all the needle dead space contributes a lot of injected air.
For me, waiting to pull the needle out after injecting seemed to help a lot. I just slowly count to 10 in my head before removing it.
>>
>>42418909
There's no effective dose of E that won't also start breast growth.
>>
>>42418722
If you're actually brave enough to chop them off in a hospital bathroom then sure, but that would be really fucking painful.

Injections inside the balls I would maybe assume to be easier? obviously the balls are really sensitive so you'd need some good anesthesia first. And then you'd stlil need to go to the hospital otherwise your testicles would just necrosis inside of you.

I'm interested in stirring though.

I assume any reasonabble person would tell me I'm insane for taking any of these seriously but I'm quite desperate myself so idk.
>>
>>42419314
Shoot, well is this small enough that it'll be minimal/slow?
>>
>>42419526
you have to suck it up, sorry. you can not look like a man or not have tits, you generally can't have both even with SERMs and binding. what you posted was a low enough dose to not get significant estrogenizing effects, which doesn't even get you to the first step of not looking male
>>
anyone have a way to compare equivalent doses of different forms of E?
>>
>>42420611
https://estrannai.se/
>>
>>42418909
raloxifene and nicotine maybe but youll probably still get tits and neither are good for you. nicotine is especially bad if on E
>>
>>42421824
Y tho? I chew dozens of nicotine gum daily and I'm still getting bitch tits
>>
Been taking prog that's spherical for about a year, but new prescription changed it to a football shaped one. Is it all the same?
>>
>>42424033
Idk
>>
>>42423097
i did some research and its not exactly bad any more than caffeine but it is a vasoconstricter and so with the increase clotting risk that further increases that risk. its only actually bad with oral e because it does some fucky liver enzyme thing that nukes it and also oral has an even higher clot risk. but it shouldn't matter at all with other RoA afaik

basically nicotine addiction is trading slightly elevated stress levels for being able to control stress response with use, which is a fair trade off imo. also playing off the buzz while exercising is godlike and im gonna miss it

its also a stimulant and appetite suppressant

BUT also because its a vasoconstricter it reduces oxygen transport in the skin so it makes your skin age and look wrinkly and its bad for hair follicles and contributes to balding and also acne and it slows healing and disrupts collagen

that was basically enough to convince me to quit after not really caring for a looong time and i already tapered my vape juice to under a mg gonna hit zero next week
>>
>>42424033
are they both gelcaps and absorb into the colon wall? if so yes,,,
>>
1 month hrt 3x day 2mg E sublingual + 12.5mg cypro daily
Looking at the timeline graph I feel like my 26yr hon body fucks heavy with e2 already got small breast buds, my skin got clearer and softer, body hair grows 3x slower and way thinner and even my hairline got better comparing to pics from October.
Is it normal? Maybe it’s actually not over
>>
>>42425159
Fine by me
I'll be acking one day so whattvecevr
>>
Fuck
>>
Fffuck
>>
>>42350151
I'm gonna be conquering my needlephobia today and finally switch over from sublingual. I'm letting lidocaine cream sit under a layer of saran wrap on my inject zone (thigh fat) for a little over an hour, then I'll clean it off and ice it for 10 minutes. Then I've got my autoinjector & my 27g 1/2in needles for subq. This might sound really excessive but needles freak me out so bad & I refuse to let myself be locked from more stable levels and a better outcome. Either way I'm down to less than 6 days worth of pills so its gotta be done. Pls wish me luck x.x
>>
dont want breasts but am going to do E anyway until I develop unhidable tits that force me to ack myself from the social shame
>>
>>42429849
Update: I did it!!! If you struggle w/ needles, buy an autoinjector. Instead of spending over an hour psyching myself up to dart the needle in & then rushing to inject, I only had to press a button & could then slowly push the plunger down. There was only a little bit of pressure and some stinging pain immediately after, though my injection sight is stinging a good bit 2 hours later (my first subq so maybe that's normal?). 10/10 so much easier that I can't believe its standard (only some trans guys seem to use them)
>>
>>42430655
Lmao based
>>
>3mo e
>5'10 (gigahon status)
>145 lbs
is it going to be enough if i go up to 150-155 lbs then back down ? i wanna get tits and hips and all that whatever but i just dont know if its enough weight or if going back down will make me too skinny again or if im even long enough on e yet
>>
>>42432305
Give it two more years. Keep gaining and keep taking shit like pio. Don't hondose either. Fuck yeah
>>
How doable is it to hide tits with a binder or something? I'm skinny so hoping they won't grow too big because I cannot handle people knowing I'm on E
>>
>>42432594
dont dont dont dont

just wear a sports bra and a hoodie retard
>>
>>42432666
Why not? I can't always wear a hoodie
>>
>>42432834
it will fuck you up so bad and give you horrible pains and problems and it will fuck your body and development up forever
>>
>>42432867
Fuuck I don't know how I'm gonna get away with hiding it at work then
>>
>>42432962
maybe not good advice idk but you can get on serms

trust me i had the same issue as you and i also wanted to bind but its sooo bad for u. serms slow breast growth a lot if ur scared about it but really i think you should just commit hiding boobs is a lot easier than u think
>>
>>42433007
Might be my only option at least for now. Or maybe I'll just hope E gives me very small breasts
>>
>>42432594
Wear shape wear like females do. Bodysuits are S tier for hiding titties and other feminine torso fat.
>>
guys will troon out but won't become fembrained enough to consider modern shapewear over medieval torturewear like corsets or binders lmaooo
>>
Bump retards
>>
>>42412269
someone pls :(
>>
File: light.jpg (94.9 KB)
94.9 KB
94.9 KB JPG
i ordered one vial of "Estradiol Enanthate 10mL 40mg/mL" recently, and needles to use to inject it subcutaneously. the needles i ordered are "1ml 30G 13mm" insulin needles. I've been doing 5mg injections weekly and did the third one yesterday but idk if I'm putting the wrong amount into the needle. i also want to try 6mg cause I'm scared I'm not getting a good enough dose but I've noticed changes in my fat distribution already and softness + fat developing in my chest and around my nipples and mental/mood changes.
i am really bad with the math and this is confusing to me. the 1ml syringe says "1cc units" near the bottom where the plunger is and the lines are labeled 10, 20, 30, etc starting at the top near where the needle itself is. so how much should i really be injecting if i want to inject 6mg? i asked recently in a different thread and someone told me between the second and third line after the 10 and that's what I've been doing. also is 6mg too much or is 5 good enough? i noticed changes but am getting worried that it's not enough after reading stuff other people have said (like you shouldn't even be able to cum on hrt???)
how much estrogen is enough to suppress testosterone naturally?

also not as important but i had another question, does caffeine possibly make the absorption faster since things like green tea speed up your metabolism? I'm worried that drinking too much green tea might have also made my body absorb all the estradiol quickly and that waiting 7 days for each injection is too long, especially cause i noticed myself feeling worse recently until injecting yesterday but that could be attributed to me not getting enough sleep yesterday

thank you in advance ^^
>>
>>42436111
i think i was the one who answered your question and im on week 5 with the same progression and concerns lol

my syringes say 1mL 29G and have 10, 20, 30 etc cc marks with five submarks. so i assume that means the little sub marks are like 0 2 4 6 8 -10- 12 14 16 18 -20- etc
so if you fill to between the second and third line after the ten that would be -10- 12 ~13~
the space between line 12 and 14 on mine would be the nonextent 13 which is 0.13mL*40mg/mL=5.2 mg

but you posted a picture of one with big lines ever 5 units tho https://archived.moe/lgbt/thread/42214711/#q42271592 so on that one if the picture is correct the lines are actually -10- 11 12 ~12.5~ 13
so the space inbetween 12 and 13th lines(the 2nd and 3rd after the 10) would be 12.5 units corresponding to 0.125 mL multiplied by the 40mg/mL cancel out the mLs and your left with the mg which is = 5

so if your doing between the second and third line on one with only 5 subdivisions your actually already doing 0.15 * 40 = 6mg

hopefully thats helpful and not more confusing

i found out they make really tiny syringles that are 1/3rd of a mL and i might switch so i can fuck around and do like 4.7mg accurately

i started with 4 and changed to 5 second week just gonna keep doing 5mg and get a blood test at 3 months unless i notice some kind of drastic reversal

im waiting for things to clear up "down there" as a signal the dose is correct. i think its safe to go all the way up to 8mg but i dont want to go higher blindly because i heard that doing to much can increase SHBG and neutralize the effect of E and can take a while to fix so im just assuming its working and hoping its near the ranges predicted by https://estrannai.se/

4 and 5 are what is usually recommended. im just not sure if my metabolism clears it fast or slow either way the half life is pretty long so it should go steady state at a high level for the vast majority of people
>>
>>42436111
since im literally reading righ tnow lol

>Start with 4mg estradiol enanthate weekly, and test at one to three months
https://startwith4mgestradiolenanthateweeklyandtestatonetothreemonths.com/

>A weekly dosage of 4-6mg is typical,
https://pghrt.diy/#S3.SS15

>Injectable estradiol, even as monotherapy, was effective at TT suppression in 82.6% of patients and comparable to combination therapy with an antiandrogen(s) or progestogen.
>Of the 357 patients included, median estradiol dose was 4 mg (interquartile range [IQR] 3-6),, estradiol concentration 232 pg/mL (IQR 134-371), and TT concentration 17 ng/dL (IQR 10-33). There was no significant difference in TT concentration or proportion reaching TT suppression between patients using estradiol monotherapy vs estradiol with an antiandrogen(s)
https://sci-net.xyz/10.1016/j.eprac.2025.07.002

>how much estrogen is enough to suppress testosterone naturally?
>More specifically, studies in cisgender men and transfeminine people have found that estradiol levels of around 200 pg/mL (734 pmol/L) suppress testosterone levels by about 90% on average (to ~50 ng/dL [1.7 nmol/L]),
includes graph
https://transfemscience.org/articles/transfem-intro/#gonadal-suppression
>>
>>42436111
honestly? 4mg EEn a week is very very sufficient for a lot of people.

ive heard of as little as 3mg EEn a week supressing T but ymmv and dont play with fire if you dont have to.

if you are of the school of thought that optimizing free E2% is the goal, then 4mg will put you well on your way to that.

i don't think caffeine has much bearing on hormone absorbtion. nicotine will in some cases

>>42412269
prog is really only measurably useful for breast roundness. u need to have a lot of breast tissue for prog to be useful.

i would weight cycle for another 6 or so months then intercut prog. not a lot of people use pio this early, so best documentation is patchy.

you probably could get really skinny and start it with prog (other people please chime in)

as for clobetasol, i've only seen it used late, but i dont have a reason why you couldn't add it soon. i wouldnt at it at the peak of a weight cycle to try to minimize stretch marks
>>
File: 38bfw8.jpg (4.1 KB)
4.1 KB
4.1 KB JPG
>>42436504
>soif your doing between the second and third line on one with only 5 subdivisions your actually already doing 0.15 * 40 = 6mg
FUCK YES
>4 and 5 are what is usually recommended.
do you mean days or mgs?

and thank you for helping me I'm so bad at the math for this ( T _ T )
i can't really afford blood tests rn, even the cheapest ones are like $69???
i also havwnt researched about how the half life works and stuff, from what i know it means how long it stays in your system but i wonder if stuff like your metabolism increasing from things like caffeine makes it get processed/leave your system sooner
>>
i also just read a reddit post of someone having a bad time with higher doses like 8mg and experiencing edema so they had to drop it to 4mg and something about dr powers and slow COMT which i think i have idk you have to do a dna test and plug it into some website but thats advanced honscience and i didn't pay much attention although i did feel better in the first two weeks than now but that might just be life and placebo and starting euphoria. i just hope im not getting some kind of rebound where T is on the ropes and fighting back.

so yeah im aiming high like steady above 300pg/mL just to be sure after initially thinking id just do minimum recommendation because i was scared now im scared its not enough. but you wanna min max to reduce side effects and also save on supplies conserve money. like ideally you would get to test every week and dial it in so you take the minimum dose to get the max suppression but still bottom of female range instead of zero and afiak its not exactly linear so its not like if you are at 400pg/mL E2 at 4mg a week you can just drop to 3mg and hit 300pg/mL since everything interacts with everything else
>>
>>42436516
>Injectable estradiol, even as monotherapy, was effective at TT suppression in 82.6% of patients and comparable to combination therapy with an antiandrogen(s) or progestogen.
>There was no significant difference in TT concentration or proportion reaching TT suppression between patients using estradiol monotherapy vs estradiol with an antiandrogen(s)
:D
ty also for the second one that says which exact estradiol levels suppress testosterone

>>42436523
>i don't think caffeine has much bearing on hormone absorbtion.
yay, thank you :D
I FUCKING LOVE GREEN TEA so I'm gonna keep drinking it then. I thought it might because it increases your metabolism
I don't take nicotine or any intoxicants anyway aside from caffeine
>>
>>42436578
>do you mean days or mgs?
4-5mg per 7 days. the guide i follow says 4mg and another popular one icbf to find says 5mg
>i can't really afford blood tests rn, even the cheapest ones are like $69???
yeah me too except ive only looked at the OP links and its like $200 and a 4 hour drive away. i might be covered by poor people health insurance at the local clinic tho id rather not talk to them and might just save up for the online scheduling psuedo-anon one. plus i want to get DHT tested and its like a $100 add on. probably gonna skip it and just pray for the hairline since i dont want fin side effects anyway. fingers crossed waiting 3 months proves i dont need to test it

>and thank you for helping me I'm so bad at the math for this
i had to go back and screenshot the post cause i fucked up my own lmao. i know the formulas but i keep having to double and triple check for ocd paranoia
>>
how much can hrt do for your hairline? mine got nuked the day my balls dropped..
>>
>>42436683
hrt can revive some DHT damaged hair follicles.

however the hairline ascension that happens during puberty is due to the skull getting bigger
>>
>>42436871
>hrt can revive some DHT damaged hair follicles
by how much? does the severity or the balding or the speed at which it happened matter more for this?
>however the hairline ascension that happens during puberty is due to the skull getting bigger
i wish it was that in my case. proper norwooding at 15 can you believe that?
>>
>>42436915
sooner is better than later bbg
>>
>>42425275
I'm on a similar dosage of 2x mg E subingual and 12.5mg cypro daily, even been on it for a month but shouldn't you wait till like the fourth or fifth month to up the dosage of E to 6mg daily? You should also look into getting the cypro dosage lowered if you're testosterone levels are at around the < 50 ng/dl range, it's also reacting well with me but well, I'm not exactly starting out as a 26yr old hon, I started out at 19 before I get to a point of no return lol
>>
Can someone give me a rundown on hydroxyprog vs medroxyprog when it comes to synthetic progestins?
>>
>>42436516
i have access to cypionate atm can i just do 5mg ec weekly instead or is ec that much worse
also i haven't gotten my levels tested in months
>>
>>42437796
medroxy is pointless in the capacity that it has the same pitfalls of bioidentical so theres not a reason to take it over P4 (other than the dosing is harder because less people are on it)

hydroxy actually has less androgenic potential so if P4 isnt working and ur willing to inject it go for it.
>>
>>42440107
I am looking into hydroxy specifically because P4 might be metabolizing into DHT for me. Gonna do labs soon to confirm this, but last time (before starting Dutasteride) my T was like, sub 10ng/dL but my DHT was 20ng/dL.
>>
>>42440119
very well could be.

i will additionally advice that dutasteride will hamper T to DHT but notably there is a backdoor pathway from prog to DHT that bypasses T altogether, making spiro the only remaining treatment.

though hydroxy can be used. you probably have seen dosing guides before but ive heard 250mg once per month
>>
>>42440162
Yeah I was also gonna use the monthly injection to prog cycle for my boobs. Do that for a bit and then pio/clob.
>>
can't hide them under layers of clothing anymore
>>
>>42440365
Based!
>>
File: file.png (92.8 KB)
92.8 KB
92.8 KB PNG
>>42439955
yeah thats fine cypionate has a similar curve to enanthate its probably equal or slightly second best imo just cause its a little spikier so peak and trough are higher and lower but average and duration is the same. but maybe thats better than smooth and steady for being more like a natural cycle who knows.theyre like rely close at least thats true for cypionate in oil not suspension



this one says they are the same
https://transfemscience.org/misc/injectable-e2-simulator-advanced/

this one says its a few percent lower
https://estrannai.se/

https://transfemscience.org/articles/injectable-e2-meta-analysis/#estradiol-cypionate-oil

https://pghrt.diy/#S3.SS13
>>
how long can you keep E vials safely out of the fridge?
>>
>>42441186
E Vials aren't supposed to be refrigerated
>>
>>42441213
they arent?
did i make it up? i could swear i've read it somewhere
>>
>>42441224
Nope, room temperature and no sunlight is ideal
>>
>>42418722
please dont
whats even the point? its probably pointless even letting a doctor do it
>>
How do my levels look? Is my estradiol too high or is it about right?
>>
Also for reference I'm on 8mg/7 days EV intramuscular with 100mg prog nightly
>>
>>42441608
How far into the shot cycle did you do your test?
>>
>>42441644
At trough
>>
>>42441683
That's very high. Recommend cutting to 6mg.
>>
>>42441625
You're going nuclear on the E
>>
how high does estradiol need to be if i had an orchi?
>>
>>42443064
Trough should be at least 100pg/mL probably no more than 250pg/mL.

4-6mg/wk injections of your chosen water would be fine.
>>
>>42441608
u look fine. u could cut back but ur fine and this might give u higher free E2%

>>42443123
no more than 250pg/mL? lol this isnt ar em tee eff.

real cap is closer to 750pg/mL in 95% of ppl per powers
>>
>>42443781
For trough levels? You're gonna destroy your body with pregnancy doses if that's your trough.
>>
>>42443123
im on 5mg/wk and my labs at trough came back at 180pg/ml but they had been higher previously before the orchi and i didn't change my dose at all
>>
>>42443916
There's always variance but you'll be fine on those levels.
>>
>>42443953
thank you anon!
>>
Does anyone have experience with this very specific brand of Progynova?
I can't access the German made one without a prescription.
>>
>>42443856
pregnancy levels are thousands to tens of thousands and mostly estrene....

dont get me wrong more might not be better but higher can give better free E2% availability.

>>42444177
its just oral EV i think
>>
>>42444342
I know what it is. I just don't know if I can trust this particular manufacturer (you will notice it has the name written in Hindi and let's just say that I'm shy about trusting some stuff from India).
>>
>>42444177
I'm >>42440365
I got here on that and spiro, it's been just 8 months but it's really effective when taken sublingually.
>>
Oh wait mine is the German one lol
try it out, maybe it's a good generic.
>>
>LH
>FSH
>TSH
>estradiol
>testosterone
>prolactin
is this what im supposed to get when im getting bloodwork done? like is it missing anything?
>>
>>42444443
EV is still EV even if its made in a broke ahh country

>>42445074
honestly dont NEED the first 3 unless ur having issues but free E2% is a must as well and maybe DHT if ur on prog
>>
>>42443781
>real cap is closer to 750pg/mL in 95% of ppl per powers
got a link pls?
>>
>>42445867
i honestly just copypasted the things they test for in the hornonal test at a lab. its okay if some things are not needed.
are you sure free E2% isnt included in the "estradiol" part though? maybe they wrote only "estradiol" so that it was retard proof, idk. i really dont want to seem sus lol.
>>
>>42445895
he yaps about it on his sub r/drwillpowers its under the pinned sidebar for guides its in the most up to date one

>>42446419
when u get estradiol tested u get gross E2 tested, not free E2%. you need both high enough gross and as high as possible free E2%
>>
Fuuuuck
>>
>>42350151
can the 100mg p-3 pills (https://www.drugs.com/imprints/p-3-28498.html) be used rectally? its just what i was prescribed (i get prescriptions for free and im poor so cant rly diy anything)
>>
how bad is it if i never get my levels tested
i'm too scared to order from privatemdlabs and go get a blood test
>>
>>42411398
AIPCTShop sells sheets of ten 30mg pioglitazone pills for $1.2 each.
>>
What are some good ftm diy sources in the US
>>
what is the target level of free e? I understand higher is better but I don't know what's considered a good minimum
everyone that talks about it gives 2% as a goal, but 2% of 150 is lower than 1% of 400
>>
My friend had an orchi and has crazy low energy. How can she microdose T to maybe help recover it ?
>>
>>42448649
Keep DIYing
better than nothing
>>
Is it normal for my posture to change on hrt?
I dunno if its some psychology or if its the hormones.
>>
>>42418722
Where are u at ? In eu maybe ? I might be able to help
>>
>>42450365
Hell yeah
>>
>>42418722
Keep your bits you fool
so much sexier that way
or get one of the eunuch maker guys to do it
>>
>>42450498
lmao are you a eunuch maker?
>>
>>42354402
You're not supposed to take E with ralox
>>
>>42450537
Nah but someone whos super into it and also into trannies.
So I wouldnt mind lol
>>
>>42450578
Sounds hot af
ever done it before to someone?
>>
>>42450627
Heh Im glad u like it. Im also rly into ballbusting and similar stuff..
And nah sadly not coz its almost impossible to find ppl into it HOWEVER Ive found an older fag thats into it and I might get to finally do it on him but sadly it wont be soon nor am I into guys.. but its better than nothing.
>>
File: Huuyyy.jpg (106.3 KB)
106.3 KB
106.3 KB JPG
>>42450657
I'd love to give myself up to you. How would you go about taking my bits away? Give me something to fantasize about :3
>>
Goddamn it why is it so fucking hard to get some estrogen pills in the EU?
And fuck me, bica is even harder to find. So many scam sites. Aaaaarrrrgh.
>>
>>42450697
Lol where are u from first ?
>>42450702
Funny thing is I can get E, T and prog all without prescription and Im from eu (but a shitty country lol)
>>
>>42450736
>but a shitty country lol
Which one? I'm from Romania. I'll travel if needed. To get the drugs, I mean.
>>
>>42450763
One in the balkans lol
U can post contact if u want and Ill add u.
>>
>>42450796
Oh come on, just tell me the country and I'll travel when the weather gets less shit.
I presume it's Slovenia or Croatia anyway. Leaning towards Slovenija because it's a femboy country anyway.
I'm not out to anyone and I don't use discord.
But e-mail me here rorepper[at]proton.me

Much appreciated if you tell me the drug store chain and what story I have to say as a foreigner.
With Romania now in Schengen too, I certainly am open to travel to bring stuff.
>>
>>42450896
Oh sry I thought u wanted me to get it for u and then u come and pick it up but Ill email u with details since u already posted it lol
>>
>>42450146
how does private lab testing even work
do i just buy it and then go to a lab and get my blood drawn before i take my injections?
what could go wrong
>>
I got the 0.75mg/1.25GM sneedhon dose of Gel, should I just do two pumps a day and say I lost a refill or something?

Reply to Thread #42350151


Supported: JPG, PNG, GIF, WebP, WebM, MP4, MP3 (max 4MB)