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>>4243628

Relevant outside reading:
https://en.wikipedia.org/wiki/Kaguya_(mouse)
2018 Chinese fatherless mouse study: https://www.sciencealert.com/genomic-imprinting-silenced-in-haploid-stem-cells-produces-fatherless-mice
Japanese in-vitro gametogenesis studies:
https://www.science.org/doi/10.1126/science.aaz6830

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>>4243630
This tall ginger dork seems to have been conceived by the Kaguya mouse method>>4246056 based on the admittedly limited information. Ericht Samaya was the donor of at least the eggs. The stem cell line to produce the sperm could have come from either Ericht or Elnora.

>>4246056
Most interesting

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OC stuff

>>4248175
Is the blonde girl the wife? Why is she lifting her shirt in the family photo?

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>>4248384
Oh damn, I forgot I even put that there, it was just the only other full color image I had of all three of them at the time.
Yeah, blonde gal is the wife, she is just really short. The family photo was a yearly redraw I do of the first pic of the tall one I ever drew. She was raising her shirt and showing off her abs, so I just drew both of them pulling up their shirts in the redraw.

pixiv doesn't seem to have the tag for 'if they mated' anymore. How do you find images like this now?

>>4251695
https://www.pixiv.net/en/tags/iPS%E7%B4%B0%E8%83%9E/artworks

>>4251708
Only 418 works?

>>4251710
And only 265 under https://www.pixiv.net/en/tags/%E3%83%87%E3%82%B6%E3%82%A4%E3%83%8A%E3%83%BC%E3%83%99%E3%83%93%E3%83%BC/artworks 'dezaina-bebi'

>>4251695
>>4251708
>>4251710
>>4251716
Thanks

>>4243623
It annoys me that the 'Science Babies' tag on AO3 was mapped to some random het Marvel ship so if you click it you get a weird mix of that and actual yuri babies.

>>4259578
Why are they bottle feeding that child?

>>4259627
WHAT are they bottle feeding that child?

Why are the kids always girls? Does this mean they will grow up to be lesbians?

>>4259635
Refer to the articles.>>4246056
There is no way for two women to have a male child. The y chromosome needed will not come out of thin air. If the option is ever allowed for the general public, all the children of lesbian couples will be female.

>>4259578
This is the correct number of kids for a two woman household though. 2 per womb.

>>4259640
Not practical in the current economy.

>>4259655
The answer would be to find a third.

>>4259628
Dr. Pepper

>>4243625

Is Shizuru or Natsuki the designated breastfeeder?

>>4259664
You don't think they would take turns?

>>4259664
>Shizuru or Natsuki
Whomst've? This is Citrus

>>4259691
That's supposed to be Citrus, not MaiHime?

>>4259694
Yes that's Yuzu and Mei

>>4259694
Those don't look remotely like Shizuru and Natsuki.

>>4259722
They don't look much like Yuzu and Mei either, the coloring is right by they have that manwah style pointy face.

>>4259724
Probably just to show them as older, this thread is all about girls that are parents after all. They aged them up

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The dilemma of science babies.

>>4260982
That and giving up the DINK lifestyle.

https://www.news-medical.net/news/20240521/Groundbreaking-study-advances-human-in-vitro-gametogenesis-for-infertility-treatment.aspx

So slow.

IVG is very powerful in that it can produce a very large quantity of sperm and produce it in a 'clean' manner- no semen or other fluids involved. This makes them highly suited for Intrauterine Insemination or IUI that uses a catheter to allow a injection of just pure saline solution to deliver the sperm directly inside the uterus. The savings in swimming time and life expectancy to the sperm is great. Plus the lab has months to grow and save very large quantities of sperm ahead of the conception attempt. The combination of the two should result in really a guaranteed conception provided the the would be mom is anywhere near accurate in determining when she is ovulating. Both the amount of sperm delivered and the time they can survive in the womb could easily be higher than natural sex with a man.
It also could be important since so far in the mouse studies, sperm produced by gonadal tissue grown from female mouse stem cells show a pronounced tendency to come out odd for a lack of a better term. Things like having short tails, oversized heads, weak swimming or only being able to swim in a circle. It hasn't stopped them from conceiving lots of baby mice with them, but they get help from gravity when combined with the target egg in a test tube conception. A very large quantity of sperm are trapped with a egg in a very small space and they get a lot of assistance from gravity.
If a male mammal was producing sperm of the quality generated in the mouse IVG studies they would be infertile for practical purposes. The distance needed to travel in normal sex which also involves swimming against gravity, would defeat them.

>>4264566
I could easily see that fertility clinics in the future would be modeled after a resort hotel. You would go there and spend two or three days. When you arrive you go to the clinic and which ever one was going to be the mom would have a catheter placed through her cervex into the uterus- and its a very small cath as little as 2.5mm diameter, no where near like getting something like a IUD put in. It should not be very uncomfortable. And the couple would collect a supply of pre loaded syringes in a warming bag. Then they would go to their room, have sex, and during or between the sex, inject the syringes through the catheter. You schedule yourself to be there for like the two nights before you figure the mom to be is going to ovulate, pick up a couple syringes each day from the clinic, so that there is always fresh sperm in large quantity in there across the whole window of time her ovulation could occur.
And the rest of the time you are there, you go to dinner, see a show, play video games. With one or both of you having a catheter going outside or submerging yourself in water in a pool or tub would not be a good thing, but you could do a lot of indoor activities without having to remove the catheter. And then when you are ready again another round of sex, more injections, ect.
If the recipient is a normal, healthy woman conception rates with this should be extremely high even if they cant fix the problem with female generated sperm being physically weaker and odd looking, just because of the quantity and placement. And a high success rate is going to be needed as this is going to be pretty expensive.
Hint for any artist who wants to tackle this kind of story.
The way things are going, the absolute necessity of conceiving a F/F baby in a test tube and then going through the risks of transplanting it into the mother seem to possibly going away. And the long periods of having to go through egg donations seem to also be going away.

>>4264571
When will this be achieved?

>>4264601
They are going so very slow. Decades. Doesn't really have to, and they have really found a LOT in the 20 years since Kaguya-hime. But- maybe another 20 years. Ultimately the real fight is to get it legalized.

bump....

>>4275317
Cute. But it happens.

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Jealous baby is jealous.

Like here Fate and Nanoha's youngest crawls out, finds the Mommas starting to have sex and wants to electrocute Nanoha-mama over possession of Fate's breasts.

>>4275485
Vivio?

>>4285366
No, not Vivio here, those two are Fate and Nanoha's biological children. Both of them are younger than Vivio's first appearance.

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This is another idea of Nanoha and Fate having a biological daughter while Vivio is still underage and living with them.

>>4243623
>When two girls really love each other they have a baby
Wrong. Babies are a result of hand holding.

Update article: https://www.sciencedirect.com/science/article/pii/S2213671124001449

>>4327749
Can this be explained more?

>>4327862
Looks like same-sex iPS cell baby research.

>>4327864
Seems like another alternative to IVF/IPS right?

>>4327862
>>4327864
>>4328051
That article I copied, because inside it, if you click on the blue colored citations in the text, they are hyperlinks that take you to other science direct articles on the topic. It had quite a few of them due to the nature of the base article.
Its a great treasure trove of links. And the base article is itself interesting (.pdf box at the top) someone actually did some basic market research in the form of questionnaires to focus groups, to see if the 'product' in question is as marketable to the public as the researchers and sci-fi fans THINK it should be. Will enough gay people be interested in having kids in this method to even go through the trouble and cost of fighting the legal battles against traditional religious groups to get this legalized.

>>4260982
Do they eventually have babies? I would like to watch her seethe as her daughter cucks her.

>>4275485
>>4288336
Is there any potential for this actually happening?

>>4330523
No they have their hand full with Vivio

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Science babies are out, Soul Gem babies are in.

>>4264626
I wonder which nation would be the first to do this.

>>4381163
Unironically? China

At first they'll try to get het couples to boost up birth rates and when that starts dying off or plateauing, they'll piviot to lesbian couples. Anything to reduce the need for immigration I think

>>4381167
I was thinking the same thing. Years ago, I would've said USA, but the country is going in a weird direction and I wouldn't be surprised if they banned such a thing

>>4381470
Irrelevant. It will only be China because every other country in the world capable of the technology bans this kind of human experimentation.

>>4381470
After China I think it'll go to Korea and Japan who are having similar issues with their aging population and the women who think the men there are losers. As for the US, they will try but once it's out of the bag they can't do anything about it. Women will fly out to do so and as long as they are both US citizens, their daughter will be too. And I've said this before, the men who will fight against it will have a harder and harder time having kids of their own.

So the US will have to let it happen whether they like it or not. It's just a matter of when

>>4381480
sure, but I thought we were discussing who would legalize the use of it, not who would invent it first

>>4381163
US, Japan, China and Europe is last.

>>4382811
No, the middle east/UAE and India will be last

>>4382942
The shittiest places. True

>>4383213
I think they'd rather ground their women into paste before letting them have kids of their own volition

>>4381470
No the US gov sees it as a money maker just like AI. Also you cant say your fighting to reverse a declining native birth rate by banning things that make it easier to have children. So last week EO's were signed making it easier to get IVF in the US. But Congress needs to follow up and actually pay for it-and what happens in 4 years is anyone's guess. For the near term it looks like the US wants to compete with China on this as with everything else.

>>4386403
Realistically who ever does it first and subsudizes it doesn't matter, they just have to so lesbians can go out and have kids en mass. Wouldn't even be bad to see straight women opt out of het relationships to have a daughter(s) with their besties

Wait a fucking minute I just realized, wouldn't it be possible for a lady to get herself pregnant with her own IPS cells??

>>4386425
Yes but would it work? Would the child effectively be a clone?
This is important knowledge.

>>4386426
I mean probably but unless you're willing to experiment on yourself, I doubt you'd get funding for it

>>4386433
>>4386434
There's potential here, girls.

>>4386426
It would likely be similar to asexual reproduction. There are species of all female lizards using parthenogenesis which we assumed meant they were exact copies of their mother but now we understand there is a scrambling of the DNA so that the daughters are not perfect clones.

>>4386426
I was always thought this was a cool concept

>>4386403
US gov hates females more than it cares about the birthrate

>>4397604
>I was always
typo, I’m not ESL

>>4397605
>US gov hates females
So truee bestie, that's why the lavender crowd needs to be aware of this as much as possible so the means of reproduction are fully controlled by them in every way imaginable
>>4397606
>I’m not ESL
That's what they all say...

>>4386424
You realize this is how Suletta came to be in Witch from Mercury.

>>4400780
Suletta is a clone of Erich not her mom

>>4397605
>goal: 150mill
US got this number from Sweden -

>150
>mill

If Swedes and US can get a 25% gain in birthrates in 15 years, with the financial stability and opportunities of these two nations, what

>>4401050
Suletta doesn't seem to be a clone at all because a clone would have had the same health problems that killed Ericht. But yet she has Erict's abilities and Nadim's skin color and personality. It reads more like the writers were influenced more by reading about Kaguya the Mouse- who was not a clone but who had the same female mouse as both her mother and 'father' which they called 'parthenogenesis' even if its not really the same as the parthenogenesis that occurs in all female species like the whiptail lizard. Because genetic recombination does occur this way there is a better chance that Ericht's health problems would not reappear, while still being similar enough that the GUND format would as accepting of Suletta as it was of Ericht.

>>4420897
This isn't really science baby material, is it now? This is either magic babies or these lizard folk can just lay eggs like that by default.

>>4435852
Pedantry.

>>4435870
Oh I'm sorry that the thread has a very specific theme. It's not my fault OP didn't make it a thread about all kinds of yuri babies.

>>4436028
Ah, I see you're a special needs kid, carry on then.

>>4436105
Have you looked in a mirror lately? Probably not, it would cause major psychic damage to yourself.

>>4436118
No, but it would to you!!

Science baby, but the baby have 4 biological mothers

>>4437242
Consider this: all science babies have four grandmothers, provided their mothers are also science babies of course.

>>4437245
Could you have a science baby with yourself?
Since it's practically cloning, does it cause inbreeding?

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>>4437247
It's only about a 50% chance of being cloning, actually. The other half of your selfcest science babies will be genetically different.

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What if bioengineered mothers instead?

Pink pill tentacle

>>4439319
we're getting into f*ta territory here

>>4439317
Looking at this...
Should we really separate sex for orgasm and procreation?

>>4437248
This is what was done with Kaguya the mouse back in 2008.

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And the Goddess of Romance said: Let there be yuri babies.

Another baby step, no pun intended.
British and Australian researchers published a paper in the New England Journal of Medicine about successfully delivering 8 babies who have three parents.
The eight mothers all have diagnosis of having or being carriers of 'genetic disorders of the mitochondria' and had been counseled against
having children due to 'high risk'.
Which is the only reason the experiment was allowed, since doing it just so two women would both be a genetic parent of the child would be 'forbidden'.
The resulting children have a mDNA mother, and a X chromosome mother.
This procedure has been talked about in these threads before, but now we have real world success. Though for political reasons they had to claim it treated a disease and there still was a man involved.
https://www.science.org/content/article/babies-born-three-parent-ivf-look-healthy-so-far-new-study-finds

>>4456806
That is still real progress, holy fuck!

If you apply this subject to Watanare, as an example.
All 5 girls could get each other pregnant using just In-vitro Gametogenesis which would require just one, admittedly painful, bone marrow draw per woman. They would only need to culture the sperm generating tissues- though those are the ones that require gene modification. So once a sufficient supply was generated it would just be a straightforward artificial insemination. No exotic procedure could be done at home, could even be done while having sex. Each of the 5 main girls could have a child with each of the others and the number of pregnancies per girl would be a completely reasonable 4. It would produce a whopping 20 children between the entire cast.

While I was playing with these numbers it occurred to me that in theory lesbian families could rival those of Catholics and Mormons in size and with comparative ease, just by alternating pregnancies.

Another thing, if Mai absolutely has to jet off to Paris or Rome the same week Renako ovulates they still won't miss the cycle. Mai's DNA is in a syringe, while it won't be sexy, she'd get inseminated. Its relatively easy to schedule compared to the 'natural' way.

>>4461942
I think at that point the only barrier would be how many lesbians and febfems don't want families because of the social pressures to be a mom growing up. So you make it inexpensive or even pay women to have as many daughters as they want (hospital fees paid for, stipend for pre, pro, and post natal care as well as baby supplies, resources for child care) would make it very enticing for many to try it at least.

And then yes you can get Sally Gearheart levels of lesbian compounds this way

>>4461946
Mai's family can afford the compound.
And Mai and her Mom would be present at every one of the girls 3/5/7 photo shoots getting ready to find modeling jobs for them...

>>4461950
>3/5/7 photo shoots
I know what you actually mean but that would be part of the grand scheme to glamorize and normalize lesbian pregnancies and families

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>>4461946
>febfems

>>4461942
>Each of the 5 main girls could have a child with each of the others and the number of pregnancies per girl would be a completely reasonable 4
I'd rather each one impregnates one other girl and gets impregnated by another one, in a closed circle.

>>4461946
>I think at that point the only barrier would be how many lesbians and febfems don't want families because of the social pressures to be a mom growing up. So you make it inexpensive or even pay women to have as many daughters as they want (hospital fees paid for, stipend for pre, pro, and post natal care as well as baby supplies, resources for child care) would make it very enticing for many to try it at least.
That still wouldn't cover mant of the expenses needed to raise a big family (not to mention the psychological stress). Only rich bitches like Mai would be able to afford these mormon families, while working-class dykes would be limited to one or two daughters.

>>4461987
That's a real term
>>4461991
>wouldn't cover mant of the expenses needed
You're right, but it would make it easier and more enticing which was the point

>>4462016
>That's a real term
And a retarded one.

>>4462017
I don't make the rules here

>>4462026
But you can choose not to use retarded terms.

>>4461991
If you refer to >>4456806
There is a way out there to keep the parent-child relationships and reduce the number of children and therefore the long term costs. But it increases the up-front costs. Embryo implantation is not something you can do at home. You would have to IVG ovarian tissue for each woman as well as making sperm generating tissue- unless you really want to go through the ordeal of induced ovulation and egg harvesting (this procedure is the number one reason women quit IVF without a child). Once you have the egg supply, you have to remove the nucleus, swap it with one from another partners egg, then fertilize it with the third partners sperm. This swapping can, in theory, be ultimately taken over by a robot that can work on filling prescriptions 24/7, but in the mean time its done by a limited number of practiced human techs. They are not doctors, but by being scarce at a technique that is more art than science and they crushed/tore/overinflated their share of ovum in learning that skill so they are not quickly replaced so they can demand big paychecks. So your not talking double, your looking at four or five times the cost to get a embryo.
But having only two kids instead of 4 could over 18 years be cheaper, and having to wrangle only two kids would be easier on the psyche and easier to find time for each kid.

>>4462036
What would you use instead?

>>4462084
Dyke, like any normal human being.

>>4462086
That's specifically for lesbians not bi women who only date women

>>4462087
There's no need to make such a pedantic distinction, there's no practical difference from a lesbian.

>>4445971
Genetically speaking of magic Yuri science babies became a thing, they would all be girls. Mothers all have xx and would always recombined to be xx in their off spring.

>>4330522
Incest yuri is fuckin amazing.

>>4462090
It's more out of respect for lesbians who aren't attracted to men at all. While bi women who only date women actively choose not to engage with men

>>4462110
'Incest' reminds me. In our hypothetical Watanare family, each child would have one full sister and 12 half siblings.
But that would leave 6 kids in the extended 'family' of 'children of women who your mom got pregnant' with no genetic relationship to them whatsoever.
But you would have to make a graph, or one of those whiteboards with lines drawn everywhere to see if thats enough for every one of the 20 girls to have a partner, after all they would have to fight for the same six girls with their one full sister who would also have that same small group as their target.

>>4461987
For some reason this term always makes me think of the February Revolution

No real news but- out of curiosity I did a web search for 'intra-uterine insemination home kid'.
The number of options already for sale on the market is amazing. How many people are buying this to have all these options? I expected the market to only be in its infancy.
Just try searching yourself.

>>4465039
>intra-uterine insemination home kit
Never heard of this before and has it really worked?

>>4465160
Well IUI works, it was a success for years in veterinary medicine before it was brought over to human medicine. And the clinical version has some clinics claiming they get better rates of pregnancy- provided they are only dealing with the males dysfunction- than natural intercourse.
Are the home kits any good? Don't know. Haven't found any sort of 'top ten list' yet with ratings. But I was just so surprised at the number of vendors offering this when we don't have access to IVG sperm from women donors yet. Yet there is, or people think their will be soon, a large number of women just using sperm banks...someone has to be buying this.

>>4466261
Oh, and if you look at the diagrams or any of the instruction videos on YouTube of how this is done. Just training cartoons with mannequin bodies but the image of entering your partner like this was quite arousing. I started to wonder 'how to write a sex scene incorporating it.
I couldn't see any obvious obstacles to it in the materials I saw. Maybe you might trade a lower rate of success per month versus something a whole lot more pleasurable and romantic?

>>4469029
I love a pregnant Miorine.

Hi. Just another news drop.
https://news.ohsu.edu/2025/09/30/ohsu-researchers-develop-functional-eggs-from-human-skin-cells

Oh. But this is even more important. And its two months old, how did I ever miss it.
https://english.kyodonews.net/articles/-/57957
"Japan gov't panel approves human embryo creation using iPS cells"
So looks like the 'race' has pushed the Japanese into trying to go from mouse to human studies without using monkey's or other primates as a in-between step.
Not sure if I like this idea.

>>4478519
It's either good or bad depending on how the wind is currently sailing in nippon land. It's not surprising but I thought they wanted to wait until the whole UN stuff blows over before pushing something like this. Or they are really, really desperate right now.

>>4478523
They are literally known for their rapidly aging population and their racism, this shouldn't be surprising

>>4478646
No, it's not surprising and it's very much welcome. Considering the two stated arguments you mentioned. However, it's surprising with the current "open" state of their government. May Madokami bless Sanae Takaichi to win all the votes.

>>4478675
It's because of those things it's emboldened them. I'll keep saying that once the pool of willing het couples and single het women dry up they'll go to bi and lesbian women couples

>>4478511
>>4478519
I worry about both these projects.
I think the Japanese are racing too fast to beat the US and the Chinese, because they want people to come to Japanese clinics to have these procedures done. Completely beside what this might mean for Japan's own population.

The US story, bothers me because they are using skin cells again. This was the source of DNA for the cloned sheep Dolly back in the 1990s and it is also widely held why she died at a rather young age for a sheep, with a lot of old age issues happening prematurely. Cells have a limited number of divisions before their line just dies, this is the fundamental source of aging, the exception being cancer cells that can reproduce forever but grow increasingly deformed as they do so. And skin cells in particular are exposed to all sorts of radiation, chemicals, and to the percentage of ozone and O- radicals that exist in the atmosphere. This causes genetic damage to the cell, but not all cells at the same time. So your playing russian roulette that you are getting a cell with perfect genes. The only way to truly be sure with current technology destroys the cell you want to use. So you can only batch test

This is so controversial, you can't afford to have a screw up and produce any damaged children. Even when you can show that it wasn't the process but the clowns running it that were the problem, it would take decades to get public trust back, and maybe never.

>>4478762
How bad is this really?

>>4478762
1 or 2 idiots will ruin it for everyone

>>4480200
>1 or 2 idiots will ruin it for everyone
Can we say inflitrators are trying to destroy eugenics programs on purpose then.

>>4478762
That problem isn't exclusive to the quality of the sperm cells if we talk about female homosexual reproduction? We aren't talking about cloning here.

>>4481380
>We aren't talking about cloning here.
The truth is we are.

>>4481381
Modifying a cell to make it a reproductive cell =/= cloning

Question to anyone that know IVF, are Embroys a key to IVF why are scientists trying to get rid of Embroys since it hinders a path human cloning? What's the reason.

>>4481381
No we are not because cloning grows a whole organism from a single cell. What we are talking about is growing the germ cells that generate sperm or eggs by splitting, each cell then splitting into two eggs or two sperm, each of which has only half of the genome needed to grow a living organism. So the sexual reproduction is retained. There is no sexual reproduction in cloning, its just a copy of the original.

>>4485918
It's amazing that some artists don't get that last part. Anything women would reproduce with each other would only ever be more women

https://www.bbc.com/news/articles/c4g2vyee0zlo
"Scientists make embryos from human skin DNA for first time"

>>4486439
>Anything women would reproduce with each other would only ever be more women
I can see a future of more females being born than males by end of the century.

>>4492273
>by end of the century
If we make it that far.

>>4492273
Thanks to the wonders of industrial run off, this very well be the case long before IVG takes off due to men's sperm quantity rapidly declining

I was reading about something called "Reciprocal IVF", compared to IVF it can allow 2 women to give birth to a genetically related baby. I still find it kind of icky that a man's sperm is still needed to fertilize the eggs but ig it's better than nothing.

>>4507292
Thats this article here:>>4456806

Basics of IUI.
I can see using a home kit and incorporating it into a sex act.
https://youtu.be/gCdVsBBblY0

>>4503172
It's amazing how you reach a certain age and even your taste in yuri changes to "I want these these two happy women to have a baby". Nature is scary.

>>4515135
I'm 30 and I want my favorite yuri couples to spend all their free time fucking each other, not raising kids because if they were raising kids they wouldn't get to fuck as much.
What age does this change?

>>4515150
>implying they don't do the sensible thing and fuck when the kids are at day care
Skill issue

>>4515150
>I want my favorite yuri couples to spend all their free time fucking each other
This is how you end up with fifteen children (in an ideal alternate universe).

>>4515135
My taste has been like that for almost 2 decades now.

>>4515150
And this one too.

>>4515391
The good thing about lesbian sex is that it doesn't beget children. And even if it did, it should be entirely reliant on their will.

>>4515150
I like this remark. I have something similar circling in my head thanks to Teren and Watanare.
If children are nowhere in the picture- why not polyamory?
And also polyamory can get you a community of lovers that can partially compensate for not having children to take care of you in your old age or if you get sick or injured. Sex is a strong social bonding agent.

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